In silico analysis and experimental validation of azelastine hydrochloride (N4) targeting sodium taurocholate co‐transporting polypeptide (NTCP) in HBV therapy

OBJECTIVES: The aim of this study was to explore sodium taurocholate co‐transporting polypeptide (NTCP) exerting its function with hepatitis B virus (HBV) and its targeted candidate compounds, in HBV therapy. MATERIALS AND METHODS: Identification of NTCP as a novel HBV target for screening candidate...

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Publicat a:Cell Prolif
Autors principals: Fu, L.‐L., Liu, J., Chen, Y, Wang, F.‐T., Wen, X., Liu, H.‐Q., Wang, M.‐Y., Ouyang, L., Huang, J., Bao, J.‐K., Wei, Y.‐Q.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2014
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495540/
https://ncbi.nlm.nih.gov/pubmed/24965018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12117
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