Peroxynitrite Decomposition Catalyst Reduces Delayed Thrombolysis‐induced Hemorrhagic Transformation in Ischemia‐reperfused Rat Brains

AIM: Hemorrhagic transformation (HT) is a major complication of delayed tissue plasminogen activator (t‐PA) treatment in ischemic stroke. We aimed to explore whether peroxynitrite decomposition catalyst (PDC) could prevent such complication. METHODS: Male Sprague‐Dawley (SD) rats were subjected to m...

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Bibliographic Details
Published in:CNS Neurosci Ther
Main Authors: Chen, Han‐Sen, Chen, Xing‐Miao, Feng, Jing‐Han, Liu, Ke‐Jian, Qi, Su‐Hua, Shen, Jian‐Gang
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495263/
https://ncbi.nlm.nih.gov/pubmed/25996167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12406
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