A Distinct Advantage to Intraarterial Delivery of (89)Zr-Bevacizumab in PET Imaging of Mice With and Without Osmotic Opening of the Blood–Brain Barrier

Glioblastoma multiforme (GBM) is the most aggressive and common type of brain cancer. Five-year survival rates are below 12%, even with the most aggressive trimodal therapies. Poor blood–brain barrier (BBB) permeability of therapeutics is a major obstacle to efficacy. Intravenous administration of b...

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Dettagli Bibliografici
Pubblicato in:J Nucl Med
Autori principali: Lesniak, Wojciech G., Chu, Chengyan, Jablonska, Anna, Du, Yong, Pomper, Martin G., Walczak, Piotr, Janowski, Miroslaw
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society of Nuclear Medicine 2019
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495238/
https://ncbi.nlm.nih.gov/pubmed/30315146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.218792
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