Inhibition of G Protein‐Coupled Receptor 81 (GPR81) Protects Against Ischemic Brain Injury

AIM: Lactates accumulate in ischemic brains. G protein‐coupled receptor 81 (GPR81) is an endogenous receptor for lactate. We aimed to explore whether lactate is involved in ischemic injury via activating GPR81. METHODS: N2A cells were transfected with GFP‐GPR81 plasmids 24 h previously, and then tre...

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Publicado en:CNS Neurosci Ther
Autores principales: Shen, Zhe, Jiang, Lei, Yuan, Yang, Deng, Tian, Zheng, Yan‐Rong, Zhao, Yan‐Yan, Li, Wen‐Lu, Wu, Jia‐Ying, Gao, Jian‐Qing, Hu, Wei‐Wei, Zhang, Xiang‐Nan, Chen, Zhong
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2014
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495224/
https://ncbi.nlm.nih.gov/pubmed/25495836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12362
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