Mitochondrial Uncoupling Protein 2 Knock-out Promotes Mitophagy to Decrease Retinal Ganglion Cell Death in a Mouse Model of Glaucoma

Glaucoma is a neurodegenerative disorder characterized by mitochondrial dysfunction and an increase in oxidative damage, leading to retinal ganglion cell (RGC) death. The oxidative status of RGCs is regulated intrinsically and also extrinsically by retinal glia. The mitochondrial uncoupling protein...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Hass, Daniel T., Barnstable, Colin J.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495138/
https://ncbi.nlm.nih.gov/pubmed/30814312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2702-18.2019
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