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Mitochondrial Uncoupling Protein 2 Knock-out Promotes Mitophagy to Decrease Retinal Ganglion Cell Death in a Mouse Model of Glaucoma

Glaucoma is a neurodegenerative disorder characterized by mitochondrial dysfunction and an increase in oxidative damage, leading to retinal ganglion cell (RGC) death. The oxidative status of RGCs is regulated intrinsically and also extrinsically by retinal glia. The mitochondrial uncoupling protein...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Neurosci
मुख्य लेखकों: Hass, Daniel T., Barnstable, Colin J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Society for Neuroscience 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495138/
https://ncbi.nlm.nih.gov/pubmed/30814312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2702-18.2019
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