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Local Anesthetic Lidocaine Inhibits TRPM7 Current and TRPM7‐Mediated Zinc Toxicity
BACKGROUND: Previous study demonstrated that overstimulation of TRPM7 substantially contributes to zinc‐mediated neuronal toxicity. Inhibition of TRPM7 activity and TRPM7‐mediated intracellular Zn(2+) accumulation may represent a promising strategy in the treatment of stroke. AIMS: To investigate wh...
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| Publicado no: | CNS Neurosci Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6495118/ https://ncbi.nlm.nih.gov/pubmed/25169754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12318 |
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