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Preclinical Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antifungal Activity of Liposomal Amphotericin B

The improved safety profile and antifungal efficacy of liposomal amphotericin B (LAmB) compared to conventional amphotericin B deoxycholate (DAmB) is due to several factors including, its chemical composition, rigorous manufacturing standards, and ability to target and transit through the fungal cel...

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Bibliographic Details
Published in:Clin Infect Dis
Main Authors: Adler-Moore, Jill, Lewis, Russell E, Brüggemann, Roger J M, Rijnders, Bart J A, Groll, Andreas H, Walsh, Thomas J
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6495008/
https://ncbi.nlm.nih.gov/pubmed/31222254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz064
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