Safety, Tolerability, and Pharmacokinetics of Liposomal Amphotericin B in Immunocompromised Pediatric Patients

The safety, tolerability, and pharmacokinetics of the liposomal formulation of amphotericin B (L-AMB) were evaluated in 40 immunocompromised children and adolescents. The protocol was an open-label, sequential-dose-escalation, multidose pharmacokinetic study with 10 to 13 patients in each of the fou...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Seibel, Nita L., Shad, Aziza T., Bekersky, Ihor, Groll, Andreas H., Gonzalez, Corina, Wood, Lauren V., Jarosinski, Paul, Buell, Donald, Hope, William W., Walsh, Thomas J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2017
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278758/
https://ncbi.nlm.nih.gov/pubmed/27855062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01477-16
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