A DNA Vaccine Encoding the Gn Ectodomain of Rift Valley Fever Virus Protects Mice via a Humoral Response Decreased by DEC205 Targeting

The Rift Valley fever virus (RVFV) is responsible for a serious mosquito-borne viral disease in humans and ruminants. The development of a new and safer vaccine is urgently needed due to the risk of introduction of this arbovirus into RVFV-free continents. We recently showed that a DNA vaccine encod...

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Опубликовано в: :Front Immunol
Главные авторы: Chrun, Tiphany, Lacôte, Sandra, Urien, Céline, Richard, Charles-Adrien, Tenbusch, Matthias, Aubrey, Nicolas, Pulido, Coralie, Lakhdar, Latifa, Marianneau, Philippe, Schwartz-Cornil, Isabelle
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494931/
https://ncbi.nlm.nih.gov/pubmed/31105695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00860
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