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HDAC Regulates Transcription at the Outset of Axolotl Tail Regeneration

Tissue regeneration is associated with complex changes in gene expression and post-translational modifications of proteins, including transcription factors and histones that comprise chromatin. We tested 172 compounds designed to target epigenetic mechanisms in an axolotl (Ambystoma mexicanum) embry...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Voss, S. Randal, Ponomareva, Larissa V., Dwaraka, Varun B., Pardue, Kaitlin E., Baddar, Nour W. Al Haj, Rodgers, A. Katherine, Woodcock, M. Ryan, Qiu, Qingchao, Crowner, Anne, Blichmann, Dana, Khatri, Shivam, Thorson, Jon S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494824/
https://ncbi.nlm.nih.gov/pubmed/31043677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43230-6
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