HDAC Regulates Transcription at the Outset of Axolotl Tail Regeneration

Tissue regeneration is associated with complex changes in gene expression and post-translational modifications of proteins, including transcription factors and histones that comprise chromatin. We tested 172 compounds designed to target epigenetic mechanisms in an axolotl (Ambystoma mexicanum) embry...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Voss, S. Randal, Ponomareva, Larissa V., Dwaraka, Varun B., Pardue, Kaitlin E., Baddar, Nour W. Al Haj, Rodgers, A. Katherine, Woodcock, M. Ryan, Qiu, Qingchao, Crowner, Anne, Blichmann, Dana, Khatri, Shivam, Thorson, Jon S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494824/
https://ncbi.nlm.nih.gov/pubmed/31043677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43230-6
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