HDAC Regulates Transcription at the Outset of Axolotl Tail Regeneration

Tissue regeneration is associated with complex changes in gene expression and post-translational modifications of proteins, including transcription factors and histones that comprise chromatin. We tested 172 compounds designed to target epigenetic mechanisms in an axolotl (Ambystoma mexicanum) embry...

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Udgivet i:Sci Rep
Main Authors: Voss, S. Randal, Ponomareva, Larissa V., Dwaraka, Varun B., Pardue, Kaitlin E., Baddar, Nour W. Al Haj, Rodgers, A. Katherine, Woodcock, M. Ryan, Qiu, Qingchao, Crowner, Anne, Blichmann, Dana, Khatri, Shivam, Thorson, Jon S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494824/
https://ncbi.nlm.nih.gov/pubmed/31043677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43230-6
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