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Effects of imidazoline I(2) receptor agonists on reserpine-induced hyperalgesia and depressive-like behavior in rats

Pharmacotherapies for fibromyalgia treatment are lacking. This study examined the antinociceptive and antidepressant-like effects of imidazoline I(2) receptor (I(2)R) agonists in a reserpine-induced model of fibromyalgia in rats. Rats were treated for three days with vehicle or reserpine. The von Fr...

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Detalhes bibliográficos
Publicado no:Behav Pharmacol
Main Authors: Siemian, Justin N., Shang, Li, Seaman, Robert W., Zhu, Qing, Zhang, Yanan, Li, Jun-Xu
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494737/
https://ncbi.nlm.nih.gov/pubmed/30383551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0000000000000454
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