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Antinociceptive Interactions between the Imidazoline I(2) Receptor Agonist 2-BFI and Opioids in Rats: Role of Efficacy at the μ-Opioid Receptor
Although μ-opioids have been reported to interact favorably with imidazoline I(2) receptor (I(2)R) ligands in animal models of chronic pain, the dependence on the μ-opioid receptor ligand efficacy on these interactions had not been previously investigated. This study systematically examined the inte...
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| Publicado en: | J Pharmacol Exp Ther |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4885507/ https://ncbi.nlm.nih.gov/pubmed/27056847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.232421 |
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