Phenotypic landscape of schizophrenia-associated genes defines candidates and their shared functions

Genomic studies have identified hundreds of candidate genes near loci associated with risk for schizophrenia. To define candidates and their functions, we mutated zebrafish orthologs of 132 human schizophrenia-associated genes. We created a phenotype atlas consisting of whole-brain activity maps, br...

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Vydáno v:Cell
Hlavní autoři: Thyme, Summer B., Pieper, Lindsey M., Li, Eric H., Pandey, Shristi, Wang, Yiqun, Morris, Nathan S., Sha, Carrie, Choi, Joo Won, Herrera, Kristian J., Soucy, Edward R., Zimmerman, Steve, Randlett, Owen, Greenwood, Joel, McCarroll, Steven A., Schier, Alexander F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494450/
https://ncbi.nlm.nih.gov/pubmed/30929901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.01.048
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