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Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration

Axon degeneration sculpts neuronal connectivity patterns during development and is an early hallmark of several adult-onset neurodegenerative disorders. Substantial progress has been made in identifying effector mechanisms driving axon fragmentation, but less is known about the upstream signaling pa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Wang, Guiping, Simon, David J, Wu, Zhuhao, Belsky, Deanna M, Heller, Evan, O'Rourke, Melanie K, Hertz, Nicholas T, Molina, Henrik, Zhong, Guisheng, Tessier-Lavigne, Marc, Zhuang, Xiaowei
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494423/
https://ncbi.nlm.nih.gov/pubmed/31042147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38730
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