Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer: The PROPHECY Study

PURPOSE: Androgen receptor splice variant 7 (AR-V7) results in a truncated receptor, which leads to ligand-independent constitutive activation that is not inhibited by anti-androgen therapies, including abiraterone or enzalutamide. Given that previous reports suggested that circulating tumor cell (C...

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Detaylı Bibliyografya
Yayımlandı:J Clin Oncol
Asıl Yazarlar: Armstrong, Andrew J., Halabi, Susan, Luo, Jun, Nanus, David M., Giannakakou, Paraskevi, Szmulewitz, Russell Z., Danila, Daniel C., Healy, Patrick, Anand, Monika, Rothwell, Colin J., Rasmussen, Julia, Thornburg, Blair, Berry, William R., Wilder, Rhonda S., Lu, Changxue, Chen, Yan, Silberstein, John L., Kemeny, Gabor, Galletti, Giuseppe, Somarelli, Jason A., Gupta, Santosh, Gregory, Simon G., Scher, Howard I., Dittamore, Ryan, Tagawa, Scott T., Antonarakis, Emmanuel S., George, Daniel J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Clinical Oncology 2019
Konular:
ORIGINAL REPORTS
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494355/
https://ncbi.nlm.nih.gov/pubmed/30865549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.01731
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