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The Preclinical Properties of a Novel Group II Metabotropic Glutamate Receptor Agonist LY379268
Activation of group II metabotropic glutamate (mGlu2/3) receptors reduces excessive glutamate release that is often associated with neurodegenerative and psychiatric disorders. This finding encouraged the search for potent and selective agonists as potential therapeutic agents. The search led to the...
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| Опубликовано в: : | CNS Drug Rev |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Publishing Inc
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6494167/ https://ncbi.nlm.nih.gov/pubmed/18078428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2007.00024.x |
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