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The Pharmacology of Ro 64‐6198, a Systemically Active, Nonpeptide NOP Receptor (Opiate Receptor‐Like 1, ORL‐1) Agonist with Diverse Preclinical Therapeutic Activity

The NOP receptor (formerly referred to as opiate receptor‐like 1, ORL‐1, LC132, OP(4), or NOP(1)) is a G protein–coupled receptor that shares high homology to the classic opioid MOP, DOP, and KOP (mu, delta, and kappa, respectively) receptors and was first cloned in 1994 by several groups. The NOP r...

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Библиографические подробности
Опубликовано в: :CNS Drug Rev
Главный автор: Shoblock, James R.
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Inc 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494153/
https://ncbi.nlm.nih.gov/pubmed/17461893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2007.00007.x
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