Fluconazole Increases Osmotic Water Transport in Renal Collecting Duct through Effects on Aquaporin-2 Trafficking

BACKGROUND: Arginine-vasopressin (AVP) binding to vasopressin V2 receptors promotes redistribution of the water channel aquaporin-2 (AQP2) from intracellular vesicles into the plasma membrane of renal collecting duct principal cells. This pathway fine-tunes renal water reabsorption and urinary conce...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Vukićević, Tanja, Hinze, Christian, Baltzer, Sandrine, Himmerkus, Nina, Quintanova, Catarina, Zühlke, Kerstin, Compton, Friederike, Ahlborn, Robert, Dema, Alessandro, Eichhorst, Jenny, Wiesner, Burkhard, Bleich, Markus, Schmidt-Ott, Kai M., Klussmann, Enno
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2019
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493977/
https://ncbi.nlm.nih.gov/pubmed/30988011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018060668
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