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Structural basis for the activation of human procaspase-7

Caspases form a family of proteinases required for the initiation and execution phases of apoptosis. Distinct proapoptotic stimuli lead to activation of the initiator caspases-8 and -9, which in turn activate the common executioner caspases-3 and -7 by proteolytic cleavage. Whereas crystal structure...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Riedl, Stefan J., Fuentes-Prior, Pablo, Renatus, Martin, Kairies, Norman, Krapp, Stephan, Huber, Robert, Salvesen, Guy S., Bode, Wolfram
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64937/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11752425/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.221580098
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