Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors

Hepatitis A virus (HAV), an enigmatic and ancient pathogen, is a major causative agent of acute viral hepatitis worldwide. Although there are effective vaccines, antivirals against HAV infection are still required, especially during fulminant hepatitis outbreaks. A more in-depth understanding of the...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Cao, Lei, Liu, Pi, Yang, Pan, Gao, Qiang, Li, Hong, Sun, Yao, Zhu, Ling, Lin, Jianping, Su, Dan, Rao, Zihe, Wang, Xiangxi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493668/
https://ncbi.nlm.nih.gov/pubmed/31039149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000229
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