Gentiopicroside Attenuates Morphine Rewarding Effect through Downregulation of GluN2B Receptors in Nucleus Accumbens

Aims: Gentiopicroside (Gent) is one of the secoiridoid compound isolated from Gentiana lutea. This compound exhibits analgesic activities and inhibits the expression of GluN2B‐containing N‐methyl‐D‐aspartate (NMDA) receptors in the anterior cingulate cortex in mice. Nucleus accumbens (NAc) is a fore...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Liu, Shui‐Bing, Ma, Lan, Guo, Hong‐Ju, Feng, Bin, Guo, Yan‐Yan, Li, Xiao‐Qiang, Sun, Wen‐Ji, Zheng, Lian‐He, Zhao, Ming‐Gao
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6493596/
https://ncbi.nlm.nih.gov/pubmed/22621711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5949.2012.00338.x
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