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Hydrocodone and Morphine Possess Similar Rewarding Effects and Reduce ERK and CREB Phosphorylation in the Nucleus Accumbens

The number of prescriptions for hydrocodone-containing opioid analgesics has greatly increased over the past decade. This increase has led to an associated enhancement in the non-medical use of hydrocodone products. There is a lack of evidence to determine the extent of the rewarding effects and sig...

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Autori principali: Tenayuca, John M., Nazarian, Arbi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418391/
https://ncbi.nlm.nih.gov/pubmed/22715022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21577
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