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Activating Cannabinoid Receptor 2 Alleviates Pathogenesis of Experimental Autoimmune Encephalomyelitis Via Activation of Autophagy and Inhibiting NLRP3 Inflammasome

AIMS: Activation of cannabinoid receptor 2 (CB2R) has been reported to ameliorate the pathogenesis of experimental autoimmune encephalomyelitis (EAE). In this study, we examined whether autophagy is involved in the beneficial effect of CB2R on EAE and explored the mechanism with a focus on inflammas...

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Vydáno v:CNS Neurosci Ther
Hlavní autoři: Shao, Bo‐Zong, Wei, Wei, Ke, Ping, Xu, Zhe‐Qi, Zhou, Jv‐Xiang, Liu, Chong
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492996/
https://ncbi.nlm.nih.gov/pubmed/25417929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12349
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