Activation of Cannabinoid Receptor 2 Ameliorates DSS-Induced Colitis through Inhibiting NLRP3 Inflammasome in Macrophages

Activation of cannabinoid receptor 2 (CB2R) ameliorates inflammation, but the underlying mechanism remains unclear. In the present study, we examined whether activation of CB2R could suppress the nucleotide-binding domain and leucine-rich repeat protein 3 (NLRP3) inflammasome. In peritoneal macropha...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ke, Ping, Shao, Bo-Zong, Xu, Zhe-Qi, Wei, Wei, Han, Bin-Ze, Chen, Xiong-Wen, Su, Ding-Feng, Liu, Chong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017608/
https://ncbi.nlm.nih.gov/pubmed/27611972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155076
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