Synergistic inhibition of pancreatic cancer with anti-PD-L1 and c-Myc inhibitor JQ1

Human pancreatic ductal adenocarcinoma (PDAC) exhibits marginal responses to anti-PD-1/PD-L1 immunotherapy and its mechanism remains poorly understood. We have investigated the effect of anti-PD-L1 and c-Myc inhibition in PDAC. Using 87 patients with PDAC from our hospital database we found a signif...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Pan, Yu, Fei, Qinglin, Xiong, Ping, Yang, Jianyang, Zhang, Zheyang, Lin, Xianchao, Pan, Minggui, Lu, Fengchun, Huang, Heguang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492971/
https://ncbi.nlm.nih.gov/pubmed/31069140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1581529
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