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Dync1h1 Mutation Causes Proprioceptive Sensory Neuron Loss and Impaired Retrograde Axonal Transport of Dorsal Root Ganglion Neurons

BACKGROUND AND PURPOSE: Sprawling (Swl) is a radiation‐induced mutation which has been identified to have a nine base pair deletion in dynein heavy chain 1 (DYNC1H1: encoded by a single gene Dync1h1). This study is to investigate the phenotype and the underlying mechanism of the Dync1h1 mutant. METH...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Zhao, Jing, Wang, Yi, Xu, Huan, Fu, Yuan, Qian, Ting, Bo, Deng, Lu, Yan‐Xin, Xiong, Yi, Wan, Jun, Zhang, Xiang, Dong, Qiang, Chen, Xiang‐Jun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492895/
https://ncbi.nlm.nih.gov/pubmed/27080913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12552
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