The E3 Ubiquitin Ligase c‐Cbl Inhibits Microglia‐Mediated CNS Inflammation by Regulating PI3K/Akt/NF‐κB Pathway

BACKGROUND: Microglia‐mediated inflammation may play an important role in the pathophysiology progression of neurodegenerative diseases, such as Parkinson's disease (PD), but the molecular mechanisms are poorly understood. AIMS: This study sought to determine whether E3 ubiquitin ligase c‐Cbl p...

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Vydáno v:CNS Neurosci Ther
Hlavní autoři: Dong, Lin, Li, Yu‐Zhen, An, Hai‐Ting, Wang, Ya‐Long, Chen, Shi‐Hao, Qian, Yan‐Jing, Wang, Ke, Zhen, Jun‐Li, Fan, Zheng, Gong, Xiao‐Li, Zheng, Yan, Wang, Xiao‐Min
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492864/
https://ncbi.nlm.nih.gov/pubmed/27156691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12557
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