Mitochondrial dysfunction and cerebral metabolic abnormalities in patients with mitochondrial encephalomyopathy subtypes: Evidence from proton MR spectroscopy and muscle biopsy

AIMS: Accumulated evidence indicates that cerebral metabolic features, evaluated by proton magnetic resonance spectroscopy ((1)H‐MRS), are sensitive to early mitochondrion dysfunction associated with mitochondrial encephalomyopathy (ME). The metabolite ratios of lactate (lac)/Cr, N‐acetyl aspartate...

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Bibliografski detalji
Izdano u:CNS Neurosci Ther
Glavni autori: Niu, Feng‐Nan, Meng, Hai‐Lan, Chang, Lei‐Lei, Wu, Hong‐Yan, Li, Wei‐Ping, Liu, Ren‐Yuan, Wang, Hui‐Ting, Zhang, Bing, Xu, Yun
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492760/
https://ncbi.nlm.nih.gov/pubmed/28695670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12714
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