Mitochondrial dysfunction and cerebral metabolic abnormalities in patients with mitochondrial encephalomyopathy subtypes: Evidence from proton MR spectroscopy and muscle biopsy

AIMS: Accumulated evidence indicates that cerebral metabolic features, evaluated by proton magnetic resonance spectroscopy ((1)H‐MRS), are sensitive to early mitochondrion dysfunction associated with mitochondrial encephalomyopathy (ME). The metabolite ratios of lactate (lac)/Cr, N‐acetyl aspartate...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Niu, Feng‐Nan, Meng, Hai‐Lan, Chang, Lei‐Lei, Wu, Hong‐Yan, Li, Wei‐Ping, Liu, Ren‐Yuan, Wang, Hui‐Ting, Zhang, Bing, Xu, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492760/
https://ncbi.nlm.nih.gov/pubmed/28695670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12714
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