Activating α7 nicotinic acetylcholine receptor inhibits NLRP3 inflammasome through regulation of β‐arrestin‐1

AIMS: To evaluate whether activating α7 nicotinic acetylcholine receptor (α7nAChR) could inhibit the NOD‐like receptor family, pyrin domain containing 3 (NLRP3) inflammasome through regulation of β‐arrestin‐1 in monocyte/macrophage system, thus contributing to the control of neuroinflammation. METHO...

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Bibliographic Details
Published in:CNS Neurosci Ther
Main Authors: Ke, Ping, Shao, Bo‐Zong, Xu, Zhe‐Qi, Chen, Xiong‐Wen, Wei, Wei, Liu, Chong
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492746/
https://ncbi.nlm.nih.gov/pubmed/28941191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12758
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