RNAi‐mediated ephrin‐B2 silencing attenuates astroglial‐fibrotic scar formation and improves spinal cord axon growth

AIMS: Astroglial‐fibrotic scar formation following central nervous system injury can help repair blood‐brain barrier and seal the lesion, whereas it also represents a strong barrier for axonal regeneration. Intensive preclinical efforts have been made to eliminate/reduce the inhibitory part and, in...

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Veröffentlicht in:CNS Neurosci Ther
Hauptverfasser: Li, Yi, Chen, Ying, Tan, Ling, Pan, Jing‐Ying, Lin, Wei‐Wei, Wu, Jian, Hu, Wen, Chen, Xue, Wang, Xiao‐Dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492699/
https://ncbi.nlm.nih.gov/pubmed/28834283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12723
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