Mdivi-1 Inhibits Astrocyte Activation and Astroglial Scar Formation and Enhances Axonal Regeneration after Spinal Cord Injury in Rats

After spinal cord injury (SCI), astrocytes become hypertrophic, and proliferative, forming a dense network of astroglial processes at the site of the lesion. This constitutes a physical and biochemical barrier to axonal regeneration. Mitochondrial fission regulates cell cycle progression; inhibiting...

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Udgivet i:Front Cell Neurosci
Main Authors: Li, Gang, Cao, Yang, Shen, Feifei, Wang, Yangsong, Bai, Liangjie, Guo, Weidong, Bi, Yunlong, Lv, Gang, Fan, Zhongkai
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069437/
https://ncbi.nlm.nih.gov/pubmed/27807407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00241
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