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n‐butylidenephthalide treatment prolongs life span and attenuates motor neuron loss in SOD1(G93A) mouse model of amyotrophic lateral sclerosis
AIMS: To evaluate the therapeutic effects of n‐butylidenephthalide (BP) in SOD1(G93A) mouse model of amyotrophic lateral sclerosis and explore the possible mechanisms. METHODS: The SOD1(G93A) mice were treated by oral administration of BP (q.d., 400 mg/kg d) starting from 60 days of age and continui...
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| Udgivet i: | CNS Neurosci Ther |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6492644/ https://ncbi.nlm.nih.gov/pubmed/28229532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12681 |
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