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Ultralow Doses of Dextromethorphan Protect Mice from Endotoxin-induced Sepsis-like Hepatotoxicity

Dextromethorphan, a wildly used over-the-counter antitussive drug, is reported to have anti-inflammatory effects. Previously, we and others have demonstrated that dextromethorphan at micromolar doses displays potent hepatoprotective effects and enhances mice survival in a sepsis model. Moreover, we...

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Bibliografske podrobnosti
izdano v:	Chem Biol Interact
Main Authors:	Zhou, Ran, Chen, Shih-Heng, Li, Guorong, Chen, Hui-Ling, Liu, YuXin, Wu, Hung-Ming, Wang, Yubao, Feng, Jing, Hong, Jau-Shyong
Format:	Artigo
Jezik:	Inglês
Izdano:	2019
Teme:	Article
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6492266/ https://ncbi.nlm.nih.gov/pubmed/30822415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2019.02.025
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Ultralow Doses of Dextromethorphan Protect Mice from Endotoxin-induced Sepsis-like Hepatotoxicity

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