Rapamycin administration is not a valid therapeutic strategy for every case of mitochondrial disease

BACKGROUND: The vast majority of mitochondrial disorders have limited the clinical management to palliative care. Rapamycin has emerged as a potential therapeutic drug for mitochondrial diseases since it has shown therapeutic benefits in a few mouse models of mitochondrial disorders. However, the un...

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Библиографические подробности
Опубликовано в: :EBioMedicine
Главные авторы: Barriocanal-Casado, Eliana, Hidalgo-Gutiérrez, Agustín, Raimundo, Nuno, González-García, Pilar, Acuña-Castroviejo, Darío, Escames, Germaine, López, Luis C.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2019
Предметы:
Research paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492073/
https://ncbi.nlm.nih.gov/pubmed/30898651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.025
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