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Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis
Mitohormesis is an adaptive response induced by a mild mitochondrial stress that promotes longevity and metabolic health in different organisms. This mechanism has been proposed as the cause of the increase in the survival in Coq7(+/−) (Mclk1(+/−)) mice, which show hepatic reduction of COQ7, early m...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6143522/ https://ncbi.nlm.nih.gov/pubmed/30228311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32190-y |
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