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Targeting the ICOS/ICOS‐L pathway in a mouse model of established allergic asthma disrupts T follicular helper cell responses and ameliorates disease
BACKGROUND: Allergic asthma is characterized by chronic inflammation and remodelling of the airways, associated with dysregulated type 2 immune responses and allergen‐specific IgE. T follicular helper cells (T(FH)) are crucial in T‐dependent B‐cell responses and have been implicated in allergic airw...
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| Publicat a: | Allergy |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6492018/ https://ncbi.nlm.nih.gov/pubmed/30220084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.13602 |
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