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Development and validation of a TP53-associated immune prognostic model for hepatocellular carcinoma

BACKGROUND: TP53 mutation is the most common mutation in hepatocellular carcinoma (HCC), and it affects the progression and prognosis of HCC. We investigated how TP53 mutation regulates the HCC immunophenotype and thus affects the prognosis of HCC. METHODS: We investigated TP53 mutation status and R...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Long, Junyu, Wang, Anqiang, Bai, Yi, Lin, Jianzhen, Yang, Xu, Wang, Dongxu, Yang, Xiaobo, Jiang, Yan, Zhao, Haitao
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491941/
https://ncbi.nlm.nih.gov/pubmed/30885723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.022
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