Dissecting the predictive value of MAPK/AKT/estrogen-receptor phosphorylation axis in primary breast cancer to treatment response for tamoxifen over exemestane: a Translational Report of the Intergroup Exemestane Study (IES)—PathIES

PURPOSE: The prognostic and predictive values of the MAPK/AKT/ERα phosphorylation axis (pT202/T204MAPK, pT308AKT, pS473AKT, pS118ERα and pS167ERα) in primary tumours were assessed to determine whether these markers can differentiate between patient responses for switching adjuvant endocrine therapy...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Szijgyarto, Zsolt, Flach, Koen D., Opdam, Mark, Palmieri, Carlo, Linn, Sabine C., Wesseling, Jelle, Ali, Simak, Bliss, Judith M., Cheang, Maggie Chon U., Zwart, Wilbert, Coombes, R. Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
Assuntos:
Clinical Trial
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491661/
https://ncbi.nlm.nih.gov/pubmed/30680659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-018-05110-x
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