Loganin Exerts Sedative and Hypnotic Effects via Modulation of the Serotonergic System and GABAergic Neurons

Corni fructus, the fruit of Cornus officinalis Sieb. et Zucc., has been used as a tonic for the kidney in China for thousands of years. Loganin is one of the major constituents derived from Corni fructus. In this study, we revealed the sedative and hypnotic activity of loganin and investigated its m...

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Publicat a:Front Pharmacol
Autors principals: Shi, Rui, Han, Yan, Yan, Yu, Qiao, Hao-Yi, He, Jun, Lian, Wen-Wen, Xia, Cong-Yuan, Li, Ting-Li, Zhang, Wei-Ku, Xu, Jie-Kun
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491506/
https://ncbi.nlm.nih.gov/pubmed/31068813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00409
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