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Loganin Exerts Sedative and Hypnotic Effects via Modulation of the Serotonergic System and GABAergic Neurons

Corni fructus, the fruit of Cornus officinalis Sieb. et Zucc., has been used as a tonic for the kidney in China for thousands of years. Loganin is one of the major constituents derived from Corni fructus. In this study, we revealed the sedative and hypnotic activity of loganin and investigated its m...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Shi, Rui, Han, Yan, Yan, Yu, Qiao, Hao-Yi, He, Jun, Lian, Wen-Wen, Xia, Cong-Yuan, Li, Ting-Li, Zhang, Wei-Ku, Xu, Jie-Kun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491506/
https://ncbi.nlm.nih.gov/pubmed/31068813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00409
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