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FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy
RAAS inhibition has been the standard treatment for CKD for years because it can reduce proteinuria and hence retard renal function decline, but the proteinuria reduction effect is still insufficient in many patients. Podocyte foot process and slit diaphragm are the final barrier to prevent serum pr...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6491468/ https://ncbi.nlm.nih.gov/pubmed/31040292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42328-1 |
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