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FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy

RAAS inhibition has been the standard treatment for CKD for years because it can reduce proteinuria and hence retard renal function decline, but the proteinuria reduction effect is still insufficient in many patients. Podocyte foot process and slit diaphragm are the final barrier to prevent serum pr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Szu-Yuan, Chu, Pao-Hsien, Huang, Po-Hsun, Hsieh, Tsung-Han, Susztak, Katalin, Tarng, Der-Cherng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491468/
https://ncbi.nlm.nih.gov/pubmed/31040292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42328-1
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