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A binding cooperativity switch driven by synergistic structural swelling of an osmo-regulatory protein pair

Uropathogenic E. coli experience a wide range of osmolarity conditions before and after successful infection. Stress-responsive regulatory proteins in bacteria, particularly proteins of the Hha family and H-NS, a transcription repressor, sense such osmolarity changes and regulate transcription throu...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Narayan, Abhishek, Gopi, Soundhararajan, Fushman, David, Naganathan, Athi N.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491433/
https://ncbi.nlm.nih.gov/pubmed/31040281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10002-9
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