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A binding cooperativity switch driven by synergistic structural swelling of an osmo-regulatory protein pair

Uropathogenic E. coli experience a wide range of osmolarity conditions before and after successful infection. Stress-responsive regulatory proteins in bacteria, particularly proteins of the Hha family and H-NS, a transcription repressor, sense such osmolarity changes and regulate transcription throu...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Narayan, Abhishek, Gopi, Soundhararajan, Fushman, David, Naganathan, Athi N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491433/
https://ncbi.nlm.nih.gov/pubmed/31040281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10002-9
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