Mechanisms of cannabinoid CB(2) receptor-mediated reduction of dopamine neuronal excitability in mouse ventral tegmental area

BACKGROUND: We have recently reported that activation of cannabinoid type 2 receptors (CB(2)Rs) reduces dopamine (DA) neuron excitability in mouse ventral tegmental area (VTA). Here, we elucidate the underlying mechanisms. METHODS: Patch-clamp recordings were performed in mouse VTA slices and dissoc...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Main Authors: Ma, Zegang, Gao, Fenfei, Larsen, Brett, Gao, Ming, Luo, Zhihua, Chen, Dejie, Ma, Xiaokuang, Qiu, Shenfeng, Zhou, Yu, Xie, Junxia, Xi, Zheng-Xiong, Wu, Jie
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
Assuntos:
Research paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491419/
https://ncbi.nlm.nih.gov/pubmed/30952618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.040
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