Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies

BACKGROUND: Linezolid is increasingly important for multidrug-resistant tuberculosis (MDR-TB) treatment. However, among children with MDR-TB, there are no linezolid pharmacokinetic data, and its adverse effects have not yet been prospectively described. We characterised the pharmacokinetics, safety,...

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Publicat a:PLoS Med
Autors principals: Garcia-Prats, Anthony J., Schaaf, H. Simon, Draper, Heather R., Garcia-Cremades, Maria, Winckler, Jana, Wiesner, Lubbe, Hesseling, Anneke C., Savic, Rada M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490911/
https://ncbi.nlm.nih.gov/pubmed/31039153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002789
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