Enriched physical environment reverses spatial cognitive impairment of socially isolated APPswe/PS1dE9 transgenic mice before amyloidosis onset

AIMS: Social isolation increases the onset of Alzheimer's disease (AD). Environmental enrichment, a complicated social and physical construct, plays beneficial effects on brain plasticity and function. This study was designed to determine whether physical enrichment can reduce the deleterious c...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Cao, Min, Hu, Pan‐Pan, Zhang, Yan‐Li, Yan, Yi‐Xin, Shields, Christopher B., Zhang, Yi‐Ping, Hu, Gang, Xiao, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490083/
https://ncbi.nlm.nih.gov/pubmed/29274291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12790
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