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Biochemical and behavioral characterization of the double transgenic mouse model (APPswe/PS1dE9) of Alzheimer’s disease
OBJECTIVE: The double transgenic mouse model (APPswe/PS1dE9) of Alzheimer’s disease (AD) has been widely used in experimental studies. β-Amyloid (Aβ) peptide is excessively produced in AD mouse brain, which affects synaptic function and the development of central nervous system. However, little has...
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| Pubblicato in: | Neurosci Bull |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5560305/ https://ncbi.nlm.nih.gov/pubmed/21788993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-011-1015-7 |
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